Welcome to the Luca Lab website!
We are interested in understanding the genetic and molecular basis of inter-individual and inter-population differences in complex phenotypes of biomedical interest.
We combine evolutionary and functional genomics approaches to study intermediate phenotypes (e.g.: transcription factor binding, gene expression, chromatin accessibility) and how they are affected by gene-environment interactions.
We are a diverse group of people with different backgrounds, skills and strengths. We value our diversity. We care about you as human beings. We do not tolerate harassment, belittlement, or discrimination of any kind.
Interpreting coronary artery disease risk through gene-environment interactions in gene regulation.
Findley et al. https://doi.org/10.1534/genetics.119.302419
High throughput characterization of genetic effects on DNA:protein binding and gene transcription.
Kalita et al 2018 Genome Res.
Gut microbiota has a widespread and modifiable effect on host gene regulation
Richards et al. https://doi.org/10.1128/mSystems.00323-18